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Horses

What causes variation in the genetics of a horse?

Students of horse genetics should always remember that variation is caused by both heredity and the environment (and the interaction between the two). Different breeds of horses have distinctive physical features, including, for example, their average height and build, and the shape of their heads.

Does heritability vary between breeds and populations?

High heritability would be expected in a population with lots of variation for the trait. In this way, heritability scores may vary between breeds and populations and over time. Heritability is not about the DNA sequences but about the distribution of the genes and phenotypes in the population.

A more complete account of “normal” genetic variation in the horse is critical to establishing the link between genotype and phenotype (Yngvadottir et al., 2009; Genomes Project et al., 2010).

What is heritability in horses?

Heritability is the proportion of the horse’s conformation and behaviour that results from its genotype. It is only three years since the genome of the horse was fully described, but the inheritance of colour is now well understood. The colour of a foal can be accurately predicted by knowing the colour of both its parents.

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What is the relationship between genetic variation heritability and plant breeding?

Genetic Variation, Heritability, and Plant Breeding. The phenotype of a plant is determined by its genetic composition, the environment in which the plant is grown, and the interaction of genotype with environment. The challenge plant breeders face is to identify and select those plants that have genotypes conferring desirable phenotypes,…

When a trait exhibits moderate heritability what does that mean?

When a trait exhibits moderate heritability, then selection is likely to provide an economic benefit for livestock and crops. Heritability is based on a comparison of the V (GA) among related and unrelated individuals in a population and determining the resemblance among relatives.

What can genomics and paleogenomics tell us about horses?

Genetics and genomics tools have driven unexpected discoveries across diverse fields of equine research including nutrition, reproduction, and exercise physiology. Paleogenomics identified the equids found in the oldest archeological site documenting horse domestication as Przewalskis horse, a different species from modern horse breeds.

How many genetic variants are there in the horse genome?

Of these variants, 1,426 were present in genic regions of 504 genes. These variants were predicted to have a high (170 variants), moderate (644 variants) and low (612 variants) impact on phenotype, with 145 predicted to be LOF variants. Of these variants, 9,756 (9,351 SNPs, 405 indels) were homozygous in all horses.

How many different alleles in a horse?

Minor allele frequency distribution of the variants. Each individual horse had on average 5,580,202 variants (5,099,978 SNPs and 480,224 indels), with on average 1,805,127 in homozygous and 3,775,075 in heterozygous states (Table 4). There were also breed-specific differences in variant number and homozygous variant number per individual (Table 4).

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Is the horse a model species for studying Athletic phenotypes?

This report comprises the first large-scale catalog of genetic variation developed for the horse, a species with potential as a translational model for many athletic phenotypes.

What can we learn from the equine reference genome?

The equine reference genome ( Wade et al., 2009) has provided a key basis for genetic investigations in horse populations ( Rebolledo-Mendez et al., 2015; Raudsepp et al., 2019 ).

What determines a horse’s personality?

A horse’s personality and temperament are determined mainly by genetics, interactions with humans and other horses, training, and environmental factors. While every horse is unique, certain traits pop up repeatedly in some individuals. Based on these common traits, we can distinguish various horse personalities.

What is the heritability of uneven feet in horses?

Heritability estimates of foot conformation traits were moderate and ranged from 0.16 for heel height to 0.27 for hoof shape. The genetic correlation between the trait of uneven feet and performance in competition was negative but weak: -0.09 with dressage and -0.12 with showjumping.

Is the height of a horse at the withers heritable?

Withers height is a good example of a quantitative genetic trait. Horses range from very short horses (miniature) to tall horses, especially draught horses. Several studies indicated a high heritability estimate for height at the withers as well as for other stature phenotypes among many breeds [reviewed in 4 ].

What is the difference between heritability and selection intensity?

Heritability is relatively high in most traits of economic importance; therefore it is not a limiting factor in most breeding programs. Selection intensity is simply the amount of selection pressure applied for a particular trait. In other words, the difference between the horses you selected and the average of the breed.

What is heritability in biology?

Heritability. Heritability is a statistic used in the fields of breeding and genetics that estimates the degree of variation in a phenotypic trait in a population that is due to genetic variation between individuals in that population. In other words, the concept of heritability can alternately be expressed in the form…

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What is considered a low heritability score?

Heritability scores range from 0.0 to 1.0 with score less than 0.20 considered low heritability, scores of 0.21–0.40 as moderate heritability and scores above 0.40 as high heritability. When a trait exhibits low heritability, the breeder knows that some genetic improvement can be made using selection; however, progress will be slow.

What is a good heritability score for cattle?

The goal of breeders is to identify those traits that will lead to the most rapid genetic gain in the herd. Heritability scores range from 0.0 to 1.0 with score less than 0.20 considered low heritability, scores of 0.21–0.40 as moderate heritability and scores above 0.40 as high heritability.

What is the purpose of the Genome Project for horses?

Horse Genome Project The domestic horse, Equus caballus, is a member of the mammalian order Perrisodactyla. The horse genome is being sequenced for two reasons. It is expected to help identify functional genome features common to all mammals, and it will serve as a tool for researchers to better understand the diseases that affect equines.

Where did the equine genome sequencing project produce a high-quality draft sequence?

The equine genome sequencing project, performed mostly at the Broad Institute, has produced a high-quality draft sequence of a female thoroughbred horse. BAC end reads for the project were generated by the University of Veterinary Medicine, in Hanover, and the Helmholtz Centre for Infection Research in Braunschweig, Germany.

Is the horse genome sequence public?

The first draft of the horse genome sequence has been deposited in public databases and is freely available for use by biomedical and veterinary researchers around the globe, leaders of the international Horse Genome Sequencing Project announced today.

Who is the scientist who sequenced the horse genome?

A team led by Kerstin Lindblad-Toh, Ph.D., at the Eli and Edythe L. Broad Institute of the Massachusetts Institute of Technology and Harvard University, in Cambridge, Mass., carried out the sequencing and assembly of the horse genome.