- Is there a genetic disorder in a horse?
- What is the Warlander bloodline?
- What are the breed requirements for a Warlander?
- Are there any genetic tests for equine genetic disorders?
- What are the most common heritable diseases in horses?
- Can Arabian horses be used as riding horses?
- What is genetically inherited traits in horses?
- What kind of gene mutation does a Quarter Horse have?
- What are the advances in equine genetics?
- Can genetic testing for coat color in horses help predict breeding outcomes?
- Is there a genetic basis for equine diseases?
- What are the genetic tests for dilution mutations in horses?
- How many genetic diseases do we test for in horses?
- What is the best textbook on horse genetics?
- What happens when a horse has two copies of a mutation?
- What happens when a horse has a GbR mutation?
- Where do the genetic variants in the horse genome come from?
- Is it possible to predict the color and pattern of foals from breeding specific mares and stallions?
- What is the coat color of an equine?
- What is a genotyping lab for horses?
- Why sequence the genome of a horse?
- Are there any good books on horse genetics?
- What do you think about the book The horse book?
- Are there any genetic disorders in Quarter Horses?
Is there a genetic disorder in a horse?
Even behavior has its roots in the DNA, as evidenced by how certain lines are known for being calm or cantankerous. Three types of genetic disorders can occur in horses: The classic Mendelian or “simple” genetic disorder, passed from one or more parents to the offspring.
What is the Warlander bloodline?
In order to establish the Warlander bloodline, these breeding standards are defined by the IWSR. Iberian: refers to horses registered and recognized as Pura Raza EspaC1ola (Andalusian) or Lusitano, or the registered and recognized cross of these two breeds (Pure Spanish Portuguese) bloodlines.
What are the breed requirements for a Warlander?
The Registry strongly encourages breeders to breed for a height no larger than 16.2 in an effort to maintain the Warlander as a baroque type horse. Color: All solid coat colors are permitted. Roaning, Pinto, or Appaloosa, markings are not permitted.
Are there any genetic tests for equine genetic disorders?
Fortunately, a few Universities around the world have for many years been continuing their research in order to create gene tests to identify carriers of the various inherited equine genetic disorders, not only those found in Arabians. The Equine Genome Project was first completed in 2007 and regularly updated since then.
What are the most common heritable diseases in horses?
Intense selection for muscle phenotypes may also underlie the surprisingly large number of heritable muscle diseases in horses, including HYPP, PSSM1 and PSSM2, RER, MH, IMM, MFM, dystrophic and non-dystrophic myotonia, and mitochondrial myopathy 4,6,13–18.
Can Arabian horses be used as riding horses?
These horses can’t be used as riding horses or breeding horses, and are generally humanely euthanized. This is also on the AQHA list of required genetic tests. This rare disease is found in the Arabian breed. These foals have a lavender tint to their coat when born, and are very weak.
What is genetically inherited traits in horses?
GENERAL INTRODUCTION: Genetically inherited traits including those that are fatal or disabling can be found in humans and in all breeds of animals including the horse.
What kind of gene mutation does a Quarter Horse have?
Affects: Approximately 1.5 percent of all Quarter Horses and as many as 56 percent of all halter horses. Description: The mutation in the sodium channel gene causes dysfunction in a specific type of sodium ion channel. These channels are involved in generating electrical impulses associated with muscle contraction.
What are the advances in equine genetics?
Advances in equine genetics have enabled the understanding of some inherited ocular disorders and ocular manifestations and are enabling cross-species comparisons.
Can genetic testing for coat color in horses help predict breeding outcomes?
There are many examples where genetic testing for coat color in horses can an assist with predicting breeding outcomes as well as inform clinical management decisions for those coat color phenotypes with pleiotropic effects.
Is there a genetic basis for equine diseases?
A lot of the diseases you know of actually have a genetic basis. There are eleven mutations that are currently commercially tested for in the equine industry.
What are the genetic tests for dilution mutations in horses?
Current genetic tests for dilution mutations in the horse include: There are several genes responsible for white coat patterns in horses. These can occur on any base color and in combination with any dilution mutation. White spotting patterns can be divided into distributed white or patch white patterning.
How many genetic diseases do we test for in horses?
Though there are approximately ten genetic diseases that are commercially tested for today, there are a huge number of genetic diseases that we could test for down the road. As you breed, buy, and care for your horses, consider their genetic background and what’s in the best interest of the horse and the breed.
What is the best textbook on horse genetics?
The principles of genetics apply generally to all organisms, and so apply to horse genetics. A good general textbook can therefore be helpful to those particularly interested horse genetics. Archer, R.K. 1961. True haemophilia (haemophilia A) in a Thoroughbred foal. Veterinary Record 73, 338-340.
What happens when a horse has two copies of a mutation?
However, when they have two copies of the mutation (homozygous), it is believed that reduction or absence of KIT signaling occurs, affecting more than just the pigment cells. For example, horses homozygous W5, W10, and W22 are likely embryonic lethal.
What happens when a horse has a GbR mutation?
The mutation causes the cells within a horse to not recognize the GBR gene, which in turn makes its body unable to produce the GB enzyme. Without this, the horse cannot store sugar properly and they will die within days or, at maximum, 2 months.
Where do the genetic variants in the horse genome come from?
Background: The catalog of genetic variants in the horse genome originates from a few select animals, the majority originating from the Thoroughbred mare used for the equine genome sequencing project.
Is it possible to predict the color and pattern of foals from breeding specific mares and stallions?
As the research in this area progresses, it is getting easier for the interested breeder to forecast the likely color and pattern of foals from breeding specific mares and stallions. However, the genotype cannot always be determined from the observable color traits (phenotype).
What is the coat color of an equine?
Equine Coat Color Genetics 1 Base Coat Color. The basic coat colors of horses include chestnut, bay, and black. … 2 Dilution Genes. There are several genes that that have been shown to reduce the amount of pigment produced and/or reduce the amount transferred from the pigment cell to the hair … 3 White Spotting Pattern Genes.
What is a genotyping lab for horses?
Horse genotyping laboratories are usually equipped to handle forensic cases. Since the molecular basis of a horse genetic disease was first described (hyperkalemic periodic paralysis or HYPP) (Rudolph et al., 1992), there has been a steady stream of discoveries of the causative mutations for other inherited defects.
Why sequence the genome of a horse?
As horses share over 90 hereditary diseases similar to those found in humans, the sequencing of the horse genome has potential applications to both equine and human health. Further, nearly half of the chromosomes in the horse genome show conserved synteny with a human chromosome, far more than between dogs and humans.
Are there any good books on horse genetics?
Although the example isn’t unique to horse genetics, it has been reported rarely in Thoroughbreds, Quarter Horses and Standardbreds (Archer, 1961, Henninger, 1988, Hutchins et al, 1967). There are many horse genetics research papers in scientific journals, but finding good up-to-date horse genetics books that don’t cost the Earth is more difficult.
What do you think about the book The horse book?
This book seems to have a lot of information. It is very hard to telll what the author means. For a person that is already advanced in horses, this is a great read. But for us who do not understand horses, nothing is explained enough to understand.
Are there any genetic disorders in Quarter Horses?
The American Quarter Horse Association has recognized the presence of five genetic disorders in the quarter-horse breed. These disorders can also affect horses of quarter-horse ancestry. The effects of genetic disorders range from mild and manageable to severe and terminal.