Are zebra loaches aggressive?

Is a zebrafish a freshwater fish?

Zebrafish (Danio rerio) are small, freshwater fish commonly found in the tropics. Although they are native to South Asia (Nepal, India, etc), Zebrafish are among the most common aquarium fish.

What is a zebrafish used for?

The zebrafish is a member of the minnow family of fish. The zebrafish is a model organism used to study the development of vertebrates. In this regard, zebrafish are useful because the embryo is transparent, it develops outside of its mother, and its development from eggs to larvae happens in just three days.

What is the zebrafish model?

“Zebrafish: A Model for the Study of Toxicants Affecting Muscle Development and Function”. International Journal of Molecular Sciences. 17 (11): 1941. doi: 10.3390/ijms17111941.

Why use zebrafish in research?

The use of zebrafish allows us to use a less sentient animal in research. It is easy to produce mutations in zebrafish, and screening programmes have been developed to find mutations that affect particular biological systems, such as the development of the nervous system. Information adapted from AnimalResearch.info What do we study?

Can zebrafish regenerate their fins?

With regards to regeneration, Zebrafish have been shown to be capable of regenerating lost fins as well as a number of lesioned organs such as the retina, spinal cord, and the heart among a number of other tissues. As a result, Zebrafish have also become excellent models for heart regeneration studies as well as animal aging research.

Does zebrafish have a closed cardiovascular system?

Zebrafish has a closed cardiovascular system and a cardiac cycle that is highly reminiscent of human cardiovascular physiology. Zebrafish can be genetically manipulated, and their genome has been fully sequenced.

What did the zebrafish model of human melanoma reveal?

^ “Zebrafish model of human melanoma reveals new cancer gene”. Science Daily. March 23, 2011. Retrieved April 28, 2014.

How many genes are in a zebrafish?

In 2002, the Wellcome Trust Sanger Institute published on the Internet the first draft of the sequence of the zebrafish genome, which includes some 17,000 genes. Zebra Fish are small fish since adult individuals are usually between 3 and 5 cm long and 1 cm wide depending on environmental conditions.

What is the role of zebrafish in nanomedicine?

Zebrafish has been used as a preclinical model for characterization of nanomedicines as well [199]. The zebrafish cancer xenograft model is an excellent alternative for studying tumor progression and for testing novel therapeutics even in the absence of appropriate transgenic models.

Is zebrafish a model organism?

Zebrafish is recognized as an ideal model organism for investigating the cellular and molecular mechanisms underlying heart formation and regeneration. Zebrafish has a closed cardiovascular system and a cardiac cycle that is highly reminiscent of human cardiovascular physiology.

What are the shortcomings of the zebrafish model?

However, all animal models have unique shortcomings, are the zebrafish model is no exception: first, zebrafish are poikilothermal animals living under water. Nonetheless, zebrafish possess metabolic characteristics similar to humans to complement data obtained from other model organisms, including rodents.

What can zebrafish tell us about the development of vertebral column deformities?

The zebrafish is a well-established model for the study of skeletogenesis with significant potential in gerontological research. With advancing age, zebrafish frequently develop gross deformities of their vertebral column, previously ascribed to reduced trunk muscle tone.

Why do zebrafish have curly spines?

Burdine and her colleagues figured out that their curly zebrafish had defective cilia. To prove that defective cilia then led to curved spines, they made use of the curly mutation’s temperature-sensitive quirk.

What can we learn from zebrafish embryos?

Since he began using them in his research, zebrafish embryos have become very popular worldwide as a means of understanding how not only fish, but all vertebrates including people, develop from the moment that sperm fertilizes an egg.

Can fish have curly spines?

In her lab at Princeton, Rebecca Burdinekeeps a number of zebrafish with odd mutations. One of the most striking is “curly,” a mutation so severe it bends the fish’s spine into a permanent C. It looks like an extreme case of scoliosis—a sideways curvature of the spine—most common in teenage girls.

How does the zebrafish caudal fin regenerate after amputation?

After amputation, the zebrafish caudal fin robustly regenerates via formation of blastema. A blastema is a mass of proliferative and morphologically homogeneous cells that have the capability to grow and develop into a lost body part.

What can we learn from the zebrafish fin?

The zebrafish fin provides a valuable model to study the epimorphic type of regeneration, whereby the amputated part of the appendage is nearly perfectly replaced. To accomplish fin regeneration, two reciprocally interacting domains need to be established at the injury site, namely a wound epithelium and a blastema.

How does retinal regeneration work in zebrafish?

Zebrafish retinal regeneration is highly tuned to regenerate specifically the cell types that are damaged. For example, light-induced photoreceptor cell death results in the regeneration of only photoreceptors [86, 92].

Can zebrafish regrow tissue?

Indeed, following surgical, chemical or genetic ablation, zebrafish can regrow functional tissue in the heart, liver, kidneys, brain, eye and caudal fin1. Due to the external location of fins on the fish’s body, fin regeneration was the first organ to be studied to understand tissue regeneration.

Can zebrafish regenerate amputated caudal fins?

Fish can completely regenerate an amputated caudal fin 9. The caudal fin in zebrafish has a bi-lobed morphology, which can be divided into three regions: apparent dorsal and ventral lobe regions with longer fin rays and a cleft region in the middle with shorter fin rays (Supplementary Fig. S1) 10, 11, 12, 13.

Do zebrafish have positional memory?

Some studies in zebrafish have suggested that fin tissues also possess positional memory. Grafting a fin ray or a hemi-ray to a different fin region and subsequent amputation of the grafted fin ray results in a restored length similar to the original length of the donor fin region rather than that of the host fin region 14, 15, 24.

How long does it take for a zebrafish to recover from injury?

Within 2-3 weeks, zebrafish are capable of restoring a fully functional organ which reaches the same size, pattern and tissue organization as the original appendage. The caudal fin has bi-lobed anatomy and is composed of several rays which can regenerate independently from one another.

What are zebrafish used for?

Therefore, zebrafish are used more and more, for example, to study the function of genes, to create animal models for human diseases and to develop new human drugs. Adult zebrafish in the zebrafish facility at the Department of Molecular Biology and Genetics, Aarhus University, Denmark.

Why is the zebrafish a good model for Human Genetics?

The resultant observation can then be extrapolated to the human genome to see if the same mutant gene is what causes a particular human genetic disorder. Overall, Zebrafish are particularly useful as animal models due to their low cost, short breeding time, and relative similarity to humans.

What is the research value of zebrafish?

The zebrafish also has great research value as a supplement to other model organisms. An example of a beneficial synergistic is that zebrafish can be used to screen relatively quickly, cheaply and with a high resolution for phenotypic changes resulting from specific genetic manipulation.